RT Journal Article
SR Electronic
T1 ▾ Simvastatin to lower cholesterol
JF Drug and Therapeutics Bulletin
JO Drug Ther Bull
FD BMJ Publishing Group Ltd
SP 29
OP 31
DO 10.1136/dtb.28.8.29
VO 28
IS 8
YR 1990
UL http://dtb.bmj.com/content/28/8/29.abstract
AB Simvastatin (Zocor - MSD) is a new lipid-lowering drug, introduced since we last discussed hyperlipidaemia.1,2 It acts by inhibiting cholesterol synthesis and is claimed to be a breakthrough in cholesterol control. The drug is intended for adults with primary hypercholesterolaemia with a cholesterol >7.8mmol/l when other therapy has been unsuccessful or poorly tolerated. It should particularly help those with heterozygous familial hypercholesterolaemia.3