PT - JOURNAL ARTICLE ED - BMJ Publishing Group Ltd TI - ▾ Simvastatin to lower cholesterol AID - 10.1136/dtb.28.8.29 DP - 1990 Apr 17 TA - Drug and Therapeutics Bulletin PG - 29--31 VI - 28 IP - 8 4099 - http://dtb.bmj.com/content/28/8/29.short 4100 - http://dtb.bmj.com/content/28/8/29.full SO - Drug Ther Bull1990 Apr 17; 28 AB - Simvastatin (Zocor - MSD) is a new lipid-lowering drug, introduced since we last discussed hyperlipidaemia.1,2 It acts by inhibiting cholesterol synthesis and is claimed to be a breakthrough in cholesterol control. The drug is intended for adults with primary hypercholesterolaemia with a cholesterol >7.8mmol/l when other therapy has been unsuccessful or poorly tolerated. It should particularly help those with heterozygous familial hypercholesterolaemia.3